Trehan I Environmental enteropathy ADC 2016

Korpe PS Environmental enteropathy Trends in Molecular Medicine 2012

Humphrey Environmental enteropathy Lancet 2009



Environmental enteropathy: critical implications of a poorly understood condition
Korpe PS. Trends in Molecular Medicine 2012:18:328336

New insights into environmental enteric dysfunction
Trehan I. Archives Dis Childhood 2016; 0: 1-4 doi:10.1136/archdischild-2015-309534

Child undernutrition, tropical enteropathy, toilets and handwashing
Humphrey J. Lancet 2009;374:1032-1035

  • What is environmental enteropathy?
  • How does it present clinically? What is the earliest age that children show signs of environmental enteropathy?  Can a child have environmental enteropathy without diarrhoea?
  • What are the likely causes of environmental enteropathy?
  • What is the pathological appearance in the small intestine of children with environmental enteropathy?
  • How are the functions of the small intestine affected by environmental enteropathy? How does this cause disease?
  • What is bacterial translocation and how does this occur? What is LPS?
  • What is the lactose: mannitol ratio, and why does this increase in environmental enteropathy?
  • How does environmental enteropathy affect vaccine efficacy?
  • What are the best ways to treat and prevent environmental enteropathy?

May 2016 Q&A Environmental enteropathy