Antiretroviral resistance patterns in children with HIV infection
Nuttall J, Pillay V
Nuttall Antiretroviral resistance patterns in HIV affected children Current Infect Dis Reports 2019
This is an update on the patterns of HIV drug resistance in children
- Name 4 classes of HIV drugs, and 1 or 2 examples of each of these
- Define what Acquired Drug Resistance, Transmitted Drug Resistance, and Pre-treatment Drug Resistance mean
- What is the WHO resistance threshold for changing to a different empiric first-line ART therapy, and why?
- What class of HIV drugs has the highest rates of resistance in children worldwide?
- What is WHO’s recommended second-line treatment now?
- When should a child be changed from first-line therapy to second-line therapy?